Roorda Lab Publications

Refereed Articles

Prepublication Articles
Meng, G., Zhang, A., Feroldi, F., Roorda, A., Waller, L. "Depth-multiplexing spectral domain OCT for full eye length imaging with a single modulation unit." arXiv:2311.17824 (2023)
2024

Moon, B., Poletti, M., Roorda, A., Tiruveedhula, P., Liu, S.H., Linebach, G., Rucci, M., Rolland, J. “Alignment, calibration, and validation of an adaptive optics scanning laser ophthalmoscope optimized for resolving human cones in the central fovea” Applied Optics 63(3): pp730-742 (2024)

 
2023

Doyle, H.K., Herbeck, S.R., Vanston, J.E., Ng, R., Tuten, W.S., Roorda, A., “Boosting 2-Photon Vision with Adaptive Optics”, Journal of Vision 23(12) 4 doi:https://doi.org/10.1167/jov.23.12.4  (2023)

Wang, Y., Wong, J., Duncan, J.L., Roorda, A., Tuten, W.S., “Enhanced S-cone Syndrome: elevated cone counts confer supernormal visual acuity in the S-cone pathway”,  Invest. Ophthalmol. Vis. Sci. 64(10). 17 doi:https://doi.org/10.1167/iovs.64.10.17 (2023).

Vanston, J.E., Boehm, A.E., Tuten, W.S., Roorda, A., “It’s not easy seeing green: The veridical perception of small spots,” Journal of Vision 23(5) 2  doi:https://doi.org/10.1167/jov.23.5.2

Wang, Y., La, T.T., Mason, M., Tuten, W.S., Roorda, A. Case Report: Multimodal, “Longitudinal Assessment of Retinal Structure and Function Following Laser Retinal Injury”, Optometry and Vision Science 100(4): 281-288 (2023).

Williams, D.R., Burns, S.A., Miller, D.T., Roorda, A. "Evolution of adaptive optics retinal imaging [Invited]," Biomed. Opt. Express 14, 1307-1338 (2023)

Micevych, P.S., Wong, J., Zhou, H., Wang, R.K., Porco, T.C., Carroll, J., Roorda, A., Duncan, J.L., "Cone structure and function in RPGR- and USH2A-associated retinal degeneration" Am. J. Ophthalmol. (online ahead of print)

Roorda, A., Cholewiak, S.A., Bhargava, S., Ivzan, N.H., LaRocca, F., Nankivil, D., Banks, M.S. "The Visual Benefits of Correcting Longitudinal and Transverse Chromatic Aberration " Journal of Vision 23(2) 3 doi:https://doi.org/10.1167/jov.23.2.3 (2023)

Roorda, A., Tiruveedhula, P., Naseri, A., Rhee, P., Clarke, M. “FIAT: A Device for Objective, Optical Measures of Accommodation in Phakic and Pseudophakic Eyes” Trans. Vis. Sci. Tech. 12, 9. doi:https://doi.org/10.1167/tvst.12.1.9 (2023)

 
2022

Pandiyan, V., Schleufer, S., Slezak, E., Fong, J., Upadhyay, R., Roorda, A., Ng, R., Sabesan, R., “Characterizing Cone Spectral Classification by Optoretinography” Biomed. Opt. Express, 13, 6574-6594 (2022)

Mozaffari, S., Feroldi, F., LaRocca, F., Tiruveedhula, P., Gregory, P.D., Park, B.H., Roorda, A. "Retinal imaging using adaptive optics optical coherence tomography with fast and accurate real-time tracking," Biomed. Opt. Express 13, 5909-5925 (2022)

Hastings, G.D., Banks, M.S., Roorda, A. "Radial and Tangential Retinal Magnifications as Functions of Visual Field Angle Across Spherical, Oblate, and Prolate Retinal Profiles" Trans. Vis. Sci. Tech. 11(9):10. doi: https://doi.org/10.1167/tvst.11.9.10. (2022)

Condor-Montes, S., Bennett, D., Bensinger E., Rani, L., Sherkat, Y., Zhao, C., Helft, Z., Roorda, A., Green, A.J., Sheehy, C.K., “Characterizing fixational eye motion variance over time as recorded by the Tracking Scanning Laser Ophthalmoscope” Translational Vision Science & Technology February 11(35). doi:https://doi.org/10.1167/tvst.11.2.35 (2022)

Bensinger, E., Wang, Y., Roorda, A., "Patches of dysflective cones in eyes with no known disease." Invest Ophthalmol Vis Sci 63, 29. doi:https://doi.org/10.1167/iovs.63.1.29 (2022)

2021

Roorda, A., "Optoretinography is coming of age" Proceedings of the National Academy of Sciences 118.51 (2021).

Bowers, N.R.*, Gautier, J.*, Lin, S., Roorda, A., "Fixational eye movements in passive versus active sustained fixation tasks" Journal of Vision 2021, 21(11), 16. doi: https://doi.org/10.1167/jov.21.11.16.  (*co-first authors)

Shenoy, J., Fong, J., Tan, J., Roorda, A., Ng, R. “R-SLAM: Optimizing Eye Tracking from Rolling Shutter Video of the Retina” Proceedings of the IEEE/CVF International Conference on Computer Vision (ICCV), 2021, pp. 4852-4861 Project Website

Kilpelainen, M., Putnam, N.M.,Ratnam, K., Roorda, A., "The retinal and perceived locus of fixation in the human visual system" Journal of Vision, 2021, 21(11), 9. doi: https://doi.org/10.1167/jov.21.11.9 (2021)

Labishetty, V., Cholewiak, S.A., Roorda, A., Banks, M.S., "Lags and leads of accommodation in humans: Fact or fiction?" Journal of Vision, 2021, 21(3), 21. doi:https://doi.org/10.1167/jov.21.3.21 (2021)

2020

Pandiyan, V.P., Bertelli, A.M., Kuchenbecker, J., Boyle, K.C., Ling, T., Chen, Z.C., Park, B.H., Roorda, A., Palanker, D., and Sabesan, R. "The optoretinogram reveals how human photoreceptors deform in response to light." Science Advances 09(6) no.37, eabc1124 DOI: 10.1126/sciadv.abc1124 (2020)

Anderson, A.G., Ratnam, K., Roorda, A., Olshausen, B.A., “High-acuity vision from retinal image motion” Journal of Vision, 20, 34. doi:https://doi.org/10.1167/jov.20.7.34  (2020)

Singh, S., Wildsoet, C.F., Roorda, A., “Optical aberrations of guinea pig eyes.” Invest Ophthalmol Vis Sci 61(10), 39. (2020)

Chen, L., Messinger, J. D., Sloan, K. R., Wong, J., Roorda, A., Duncan, J. L., & Curcio, C. A. "Abundance and multimodal visibility of soft drusen in early age-related macular degeneration: a clinicopathologic correlation."Retina, 40(8), 1644-1648 (2020) doi: 10.1097/IAE.0000000000002893

Foote, K.G., Wong, J.J., Boehm, A.E., Bensinger, E., Porco, T.C., Roorda, A., Duncan, J.L. “Comparing Cone Structure and Function in RHO- and RPGR-Associated Retinitis Pigmentosa” Invest Ophthalmol Vis Sci 61, 22. (2020)

Mozaffari, S., LaRocca, F., Jaedicke, V., Tiruveedhula, P., and Roorda, A. "Wide-vergence, multi-spectral adaptive optics scanning laser ophthalmoscope with diffraction-limited illumination and collection" Biomedical Optics Express 11, 1617-1632 (2020)

2019

Foote, K.G., Rinella, N., Tang, J., Bensaid, N., Zhou, H., Zhang, Q., Wang, R.K., Porco, T.C., Roorda, A., and Duncan, J.L. "Cone Structure Persists Beyond Margins of Short-Wavelength Autofluorescence in Choroideremia" Invest Ophthalmol Vis Sci 60(14), 4931-4942 (2019)

Bowers, N.B., Boehm, A.E., Roorda, A., "The Effect of Fixational Tremor on the Retinal Image" Journal of Vision September 2019, Vol.19, 8. doi:10.1167/19.11.8  Supplemental materials for download

Wang, Y., Bensaid, N., Tiruveedhula, P., Ma, J., Ravikumar, S., Roorda, A., "Human foveal cone photoreceptor topography and its dependence on eye length" eLife 2019;8:e47148. DOI: https://doi.org/10.7554/eLife.47148 Supplemental materials for download

Schmidt, B.P., Boehm, A.E., Tuten, W.S., Roorda, A., "Spatial summation of individual cones in human color vision" PLoS ONE 14(7) E0211397 (2019) https://doi.org/10.1371/journal. pone.0211397

Sajdak, B.S., Salmon, A.E., Cava, J,A., Allen, K.P, Freling, S., Ramamirtham, R., Norton, T.T., Roorda, A., Carroll, J., "Noninvasive imaging of the tree shrew eye: wavefront analysis and retinal imaging with correlative histology" Experimental Eye Research 185:107683 (2019)

Bensinger, E., Rinella, N., Saud, A., Loumou, P., Ratnam, K., Griffin, S., Qin, J., Porco, T.C., Roorda, A., Duncan, J.L., "Loss of Foveal Cone Structure Precedes Loss of Visual Acuity in Patients with Rod-Cone Degeneration" Invest Ophthalmol Vis Sci 60:3187–3196. https://doi.org/ 10.1167/iovs.18-26245  (2019)

Metlapally, S., Bharadwaj, S.R., Roorda, A., Nilagiri, V.K.,  Yu, T.T., Schor C.M., “Binocular cross-correlation analyses of the effects of high-order aberrations on the stereoacuity of eyes with keratoconus.” Journal of Vision, 19(6):12 doi:10.1167/19.6.12 (2019)

Foote, K.G., De la Huerta, I., Gustafson, K., Baldwin, A., Zayit-Soudry, S., Rinella, N., Porco, T.C., Roorda, A., Duncan, J.L., “Cone spacing correlates with retinal thickness and microperimetry in patients with inherited retinal degenerations” Invest Ophthalmol Vis Sci, 60(4), 1234-1243 (2019)

Boehm, A.E., Privitera, C.M., Schmidt, B.P., Roorda, A.,  "Transverse chromatic offsets with pupil displacements in the human eye: sources of variability and methods for real-time correction" Biomedical Optics Express 10(4): 1691-1706 (2019)

2018

Qin, J., Rinella, N., Zhang, Q., Zhou, H., Wong, J., Deiner, M., Roorda, A., Porco, T.C., Wang, R.K., Schwartz, D.M., Duncan, J.L. "OCT Angiography and Cone Photoreceptor Imaging in Geographic Atrophy" Invest Ophthalmol Vis Sci, 59 (15), 5985-5992. (2018)

Schmidt, B.P., Boehm, A.E., Foote, K.G., Roorda, A., “The spectral identity of foveal cones is preserved in hue perception” Journal of Vision, 18(11):19 (2018)

Mozaffari, S., Jaedicke, V., LaRocca, F., Tiruveedhula, P., Roorda, A., "Versatile Multi-Detector Scheme for Adaptive Optics Scanning Laser Ophthalmoscopy” Biomedical Optics Express 9(11), 5477-5488 (2018)

Tuten, W.S., Cooper, R.F., Tiruveedhula, P., Dubra, A., Roorda, A., Cottaris, N.P., Brainard, D.H., & Morgan, J.I.W. “Spatial summation in the human fovea: do normal optical aberrations and fixational eye movements have an effect?” Journal of Vision, 18(8):6 (2018).

Foote, K.G., Loumou, P., Griffin, S., Qin, J., Ratnam, K., Porco, T.C., Roorda, A., Duncan, J.L., "Relationship Between Foveal Cone Structure and Visual Acuity Measured With Adaptive Optics Scanning Laser Ophthalmoscopy in Retinal Degeneration." Invest Ophthalmol Vis Sci, 59 (8), 3385-3393 (2018)

Schmidt, B.P., Sabesan, R., Tuten, W.S., Neitz, J., Roorda, A. "Sensations from a single M-cone depend on the activity of surrounding S-cones" Sci Rep, 8 (1), 8561 (2018)

Ağaoğlu, M.N., Sheehy, C.K., Tiruveedhula, P., Roorda, A., Chung, S.T.L., “Suboptimal eye movements for seeing fine details”, Journal of Vision 18 (8). doi:10.1167/18.5.8 (2018)

Lew, Y.J., Rinella, N., Qin, J., Chiang, J., Moore, A.T., Porco, T.C., Roorda, A., Duncan, J.L. “High Resolution Imaging in male germ cell associated kinase (MAK)-related Retinal Degeneration” Am J. Ophthalmol. 185(1) 32-42 (2018)

Domdei, N., Domdei, L., Reiniger,J.L., Linden, M., Holz, F.G., Roorda, A., Harmening, W.M. “Ultra-high contrast retinal display system for single photoreceptor psychophysics” Biomed. Optics Express, 9(1) 157-172 (2018)

2017

Tuten, W.S., Harmeing, W.M., Sabesan, R., Roorda, A., Sincich, L.C., "Spatiochromatic interactions between individual cone photoreceptors in the human retina", J. Neurosci., 37(39) 9498-9509 (2017)

Tu, J.H., Foote, K.G., Lujan, B.J., Ratnam, K., Qin, J., Gorin, M.B., Cunningham Jr., E.T., Tuten, W.S., Duncan, J.L., Roorda, A., “Dysflective cones: Visual function and cone reflectivity in long-term follow-up of acute bilateral foveolitis” Am J. Ophthalmol Case Reports, 7: 14-19 (2017)

Ratnam, K., Domdei, N, Harmening, W.M., Roorda, A., “Benefits of retinal image motion at the limits of spatial vision”, Journal of Vision 17(1):30. doi: 10.1167/17.1.30. (2017)

2016

Winter, S., Sabesan, R., Tiruveedhula, P., Privitera, C., Unsbo, P., Lunstrom, L., Roorda, A., “Transverse chromatic across the visual field of the human eye”, Journal of Vision, 16(14):9, 1–10 doi: 10.1167/16.14.9

Sabesan, R., Schmidt, B.P., Tuten, W.S., Roorda, A., “The elementary representation of spatial and color vision in the human retina” Science Advances, 2(9): http://dx.doi.org/10.1126/sciadv.1600797 (2016)

Privitera, C.M., Sabesan, R., Winter, S., Tiruveedhula, P., Roorda, A., “Eye-tracking technology for real-time monitoring of transverse chromatic aberration” Optics Letters, 41(8) 1728-1731 (2016)

Stevenson, S.B., Sheehy, C.K., & Roorda, A. "Binocular eye tracking with the Tracking Scanning Laser Ophthalmoscope." Vision Res, 118: 98-104 (2016)

2015

Sabesan, R., Hofer, H., & Roorda, A. "Characterizing the Human Cone Photoreceptor Mosaic via Dynamic Photopigment Densitometry." PLoS One, 10 (12), e0144891 (2015).

Roorda, A., Duncan, J.L., "Adaptive Optics Ophthalmoscopy" Annual Review of Vision Science, 1(1): 19-50 (2015).

Zayit-Soudry, S., Sippl-Swezey, N., Porco, T.C., Lynch, S.K., Syed, R., Ratnam, K., Menghini, M., Roorda, A.J., & Duncan, J.L. “Repeatability of Cone Spacing Measures in Eyes with Inherited Retinal Degenerations.” Invest Ophthalmol Vis Sci, 56 (10), 6179-6189 (2015).

Antony, B.J., Stetson, P.F., Abramoff, M.D., Lee, K., Colijn, J.M., Buitendijk, G.H., Klaver, C.C., Roorda, A., & Lujan, B.J. “Characterizing the Impact of Off-Axis Scan Acquisition on the Reproducibility of Total Retinal Thickness Measurements in SDOCT Volumes” Transl Vis Sci Technol, 4 (4), 3 (2015)

Bruce, K.S., Harmening, W.M., Langston, B.R., Tuten, W.S., Roorda, A., & Sincich, L.C. "Normal Perceptual Sensitivity Arising From Weakly Reflective Cone Photoreceptors." Invest Ophthalmol Vis Sci, 56 (8), 4431-4438 (2015)

Sheehy, C.K., Tiruveedhula, P., Sabesan, R., and Roorda, A. "Active eye-tracking for an adaptive optics scanning laser ophthalmoscope," Biomed. Opt. Express 6, 2412-2423 (2015)

Lujan, B.J., Roorda, A., Croskrey, J.A., Dubis, A.M., Cooper, R.F., Bayabo, J.K., Duncan, J.L., Antony, B.J., & Carroll, J. "Directional Optical Coherence Tomography Provides Accurate Outer Nuclear Layer and Henle Fiber Layer Measurements." Retina, 35 (8), 1511-1520 (2015)

Wang, Q., Tuten, W.S., Lujan, B.J., Holland, J., Bernstein, P.S., Schwartz, S.D., Duncan, J.L., & Roorda, A. “Adaptive Optics Microperimetry and OCT Images Show Preserved Function and Recovery of Cone Visibility in Macular Telangiectasia Type 2 Retinal Lesions.” Invest Ophthalmol Vis Sci, 56 (2), 778-786. (2015)

Menghini,M., Lujan,B.J., Zayit-Soudry,S., Syed,R., Porco,T.C., Bayabo,K., Carroll,J., Roorda,A., & Duncan,J.L. “Correlation of outer nuclear layer thickness with cone density values in patients with retinitis pigmentosa and healthy subjects.” Invest Ophthalmol.Vis.Sci., 56(1), 372-381.PM:25515570 (2015)

2014

Duncan,J.L., Biswas,P., Kozak,I., Navani,M., Syed,R., Soudry,S., Menghini,M., Caruso,R.C., Jeffrey,B.G., Heckenlively,J.R., Reddy,G.B., Lee,P., Roorda,A., & Ayyagari,R. "Ocular Phenotype of a Family with FAM161A-associated Retinal Degeneration" Ophthalmic Genet.,  1-9. (2014)

Yang, Q., Zhang, J., Nozato, K., Saito, K., Williams, D.R., Roorda, A., Rossi, E.A. "Closed-loop optical stabilization and digital image registration in adaptive optics scanning light ophthalmoscopy" Biomedical optics express, 5(9), 3174-3191 (2014)

Harmening, W.M., Tuten, W.S., Roorda, A., Sincich, L.C. "Mapping the Perceptual Grain of the Human Retina" J. Neurosci. 34(16), 5667-5677 (2014)

2013

Bowne, S.J., Sullivan, L.S., Avery, C.E., Sasser, E.M., Roorda, A., Duncan, J.L., Wheaton, D.H., Birch, D.G., Branham, K.E., Heckenlively, J.R., Sieving, P.A., Daiger, S.P. "Mutations in the small nuclear riboprotein 200 kDa gene (SNRNP200) cause 1.6% of autosomal dominant retinitis pigmentosa" Molecular Vision. 19, 2407-2417. (2013)

Zayit-Soudry, S., Duncan, J.L., Syed, R., Menghini, M., Roorda, A.J. "Cone structure imaged with adaptive optics scanning laser ophthalmoscopy in eyes with nonneovascular age-related macular degeneration" Invest Ophthalmol.Vis.Sci. 54, 7498-7509. (2013)

Arathorn, D. W., Stevenson, S. B., Yang, Q., Tiruveedhula, P., & Roorda, A. “How the unstable eye sees a stable and moving world.” Journal of Vision, 13(10):22, 1–19, http://www.journalofvision.org/content/13/10/22,  doi:10.1167/13.10.22. (2013)

Ratnam, K., Carroll, J., Porco, T.C., Duncan, J.L., Roorda, A. "Relationship between Foveal Cone Structure and Clinical Measures of Visual Function in Patients with Inherited Retinal Degenerations" Invest Ophthalmol.Vis.Sci. 54(8), 5836-5847, (2013)

Rossi,E.A., Achtman,R.L., Guidon,A., Williams,G.A., Roorda,A., Carroll,J. “Visual function and cortical organization in carriers of blue cone monochromacy”.  PLoS ONE, 8(2) e57956. doi:10.1371/journal.pone.0057956

Syed,R., Sundquist,S.M., Ratnam,K., Soudry,S.Z., Zhang,Y., Crawford,J.B., MacDondald,I.M., Godara,P., Rha,J., Carroll,J., Roorda,A., Stepien,K.E., & Duncan,J.L. “High Resolution Images of Retinal Structure in Patients with Choroideremia” Investigative Ophthalmology & Visual Science, 54(2), 950-961, (2013)

Ratnam,K., Vastinsalo,H., Roorda,A., Sankila,E.K., & Duncan,J.L. "Cone Structure in Patients with Usher Syndrome III and Mutations in the Clarin 1 Gene." JAMA Ophthalmol, 131(1), 67-74 (2013)

Braaf,B., Vienola,K., Sheehy,C.K., Yang,Q., Vermeer,K.A., Tiruveedhula,P., Arathorn,D.W., Roorda,A., & de Boer,J.F. “Real-time eye motion correction in phase-resolved OCT angiography with tracking SLO” Biomedical Optics Express, 4(1), 51-65. (2013)

2012

Duncan,J.L., Roorda,A., Navani,M., Vishweswaraiah,S., Syed,R., Soudry,S., Ratnam,K., Gudiseva,H.V., Lee,P., Gaasterland,T., Ayyagari,R. “Identification of a Novel Mutation in the CDHR1 Gene in a Family With Recessive Retinal Degeneration” Archives of Ophthalmology, 130(10), 1301-1308 (2012).

Vienola,K., Braaf,B., Sheehy,C.K., Tiruveedhula,P., Arathorn,D.W., de Boer,J.F., & Roorda,A. “Real-time eye motion compensation in OCT imaging with tracking SLO”. Biomedical Optics Express, 3(11) 2950-2963 (2012)

Hickenbotham, A., Tiruveedhula,P., Roorda, A. “Comparison of spherical aberration and small pupil profiles in improving depth of focus for presbyopic corrections," Journal of Cataract and Refractive Surgery, 38(12) (2012)

Sheehy,C.K., Yang,Q., Arathorn,D.W., Tiruveedhula,P., de Boer,J.F., & Roorda,A. “High-speed, image-based eye tracking with a scanning laser ophthalmoscope.” Biomedical Optics Express, 3(10) 2612-2622 (2012)

Harmening,W.M., Tiruveedhula,P., Roorda,A., Sincich,L.C.  “Measurement and correction of transverse chromatic offsets for multi-wavelength retinal microscopy in the living eye.” Biomedical Optics Express, 3(9), 2066-2077 (2012) [video 1: TCA_retinal_video] [video 2: TCA vs Pupil Position]

Hickenbotham, A., Roorda, A., Steinmaus, C., Glasser, A. "Meta-analysis of Gender Differences in Presbyopia" Invest Ophthalmol.Vis.Sci. 53(6):3215-3220 (2012).

Tuten, W.S., Tiruveedhula, P., Roorda, A. "Adaptive optics scanning laser ophthalmoscope-based microperimetry" Optom.Vis.Sci. 89, 563-574. (2012).

Mkrtchyan, M., Lujan, B.J., Merino, D., Thirkill, C.E., Roorda, A., Duncan, J.L. "Outer retinal structure in patients with acute zonal occult outer retinopathy" Am.J.Ophthalmol. 153, 757-768. (2012).

Tam, J., Dhamdhere, K.P., Tiruveedhula, P., Lujan, B.J., Johnson, R.N., Bearse, M.A., Jr., Adams, A.J., Roorda, A. "Subclinical capillary changes in non-proliferative diabetic retinopathy" Optom.Vis.Sci. 89, E692-E703 (2012).

2011

Duncan, J.L., Ratnam, K., Birch, D.G., Sundquist, S.M., Lucero, A.S., Zhang, Y., Meltzer, M., Smaoui, N., Roorda, A. "Abnormal cone structure in foveal schisis cavities in X-linked retinoschisis from mutations in exon 6 of the RS1 gene" Invest Ophthalmol.Vis.Sci. 52, 9614-9623. (2011).

Tam, J., Dhamdhere, K.P., Tiruveedhula, P., Manzanera, S., Barez, S., Bearse, M.A., Jr., Adams, A.J., Roorda, A. "Disruption of the Retinal Parafoveal Capillary Network in Type 2 Diabetes Prior to the Onset of Diabetic Retinopathy" Invest Ophthalmol.Vis.Sci. 52(11): 9257-9266 (2011)

Merino, D., Duncan, J.L., Tiruveedhula, P., Roorda, A., “Observation of cone and rod photoreceptors in normal subjects and patients using a new generation Adaptive Optics Scanning Laser Ophthalmoscope” Biomedical Optics Express, 2(8), 2189-2201 (2011).

Roorda, A., "Adaptive optics for studying visual function: A comprehensive review" Journal of Vision 11(5) article 6 (2011). http://www.journalofvision.org/content/11/5/6.full

Chen,Y., Ratnam,K., Sundquist,S.M., Lujan,B.J., Ayyagari,R., Gudiseva,V.H., Roorda,A., Duncan,J.L. “Cone photoreceptor abnormalities correlate with vision loss in patients with Stargardt Disease.”  Invest.Ophthalmol.Vis.Sci. 52(6), 3281-3292. (2011)

Manzanera, S., Helmbrecht, M.A.,  Kempf, C.J, Roorda, A. "MEMS segmented-based adaptive optics scanning laser ophthalmoscope," Biomed. Opt. Express 2, 1204-1217 (2011)

Talcott,K.E., Ratnam,K., Sundquist,S.M., Lucero,A.S., Lujan,B.J., Tao,W., Porco,T.C., Roorda,A., Duncan,J.L. “Longitudinal Study of Cone Photoreceptors during Retinal Degeneration and in Response to Ciliary Neurotrophic Factor Treatment” Invest Ophthalmol.Vis.Sci., 52(5), 2219-2226. (2011)

Lujan,B.J., Roorda,A., Knighton,R.W., Carroll,J. “Revealing Henle's Fiber Layer Using Spectral Domain Optical Coherence Tomography” Invest Ophthalmol.Vis.Sci., 52(3), 1486-1492. (2011)

Duncan,J.L., Talcott,K.E., Ratnam,K., Sundquist,S.M., Lucero,A.S., Day,S., Zhang,Y.,Roorda,A. “Cone Structure in Retinal Degeneration Associated with Mutations in the peripherin/RDS Gene” Invest Ophthalmol.Vis.Sci., 52(3), 1557-1566 (2011)

Tam, J., Tiruveedhula, P.,  Roorda, A. “Characterization of single-file flow through human retinal parafoveal capillaries using an adaptive optics scanning laser ophthalmoscope” Biomed. Opt. Express 2(4), 781–793 (2011)

Tam,J., Roorda,A. “Speed quantification and tracking of moving objects in adaptive optics scanning laser ophthalmoscopy”  J. Biomed Opt 16(3), 036002 (2011)

Gelfand, J.M., Duncan, J.L., Racine, C.A., Gillum, L.A., Chin, C.T., Zhang, Y., Zhang, Q., Wong, L.J., Roorda, A., Green, A.J. "Heterogeneous patterns of tissue injury in NARP syndrome" J.Neurol. 258, 440-448. (2011).

2010

Li,K.Y., Tiruveedhula,P., Roorda,A.  "Intersubject variability of foveal cone photoreceptor density in relation to eye length."  Invest Ophthalmol.Vis.Sci. 51, 6858-6867 (2010).

Godara,P., Dubis,A.M., Roorda,A., Duncan,J.L., Carroll,J. "Adaptive optics retinal imaging: emerging clinical applications".  Optom.Vis.Sci. 87, 930-941 (2010).

Putnam, N.M., Hammer, D.X., Zhang, Y., Merino, D., Roorda,A., "Modeling the foveal cone mosaic imaged with adaptive optics scanning laser ophthalmoscopy," Opt. Express 18, 24902-24916 (2010).

Rossi, E.A., Roorda, A. “Is visual resolution after adaptive optics correction susceptible to perceptual learning?” Journal of Vision 10(12): article 11, 1–14, http://www.journalofvision.org/content/10/12/11 , doi:10.1167/10.12.11. (2010).

Carroll, J. Rossi,E.A., Porter, J., Neitz, J., Roorda, A., Williams, D.R., Neitz, M.”Deletion of the X-linked Opsin Gene Array Locus Control Region (LCR) Results in Disruption of the Cone Mosaic” Vision Res. 50(19):1989-1999 (2010)

Yang, Q., Arathorn, D.W., Tiruveedhula, P., Vogel, C.R., Roorda, A., “Design of an integrated hardware interface for AOSLO image capture and cone-targeted stimulus delivery” Optics Express 18(17):17841-17858 (2010)

Tarrant, J., Roorda, A., Wildsoet, C.F., "Determining the accommodative response from wavefront aberrations" J. Vision 10-5-4 (2010)

Roorda, A. “Applications of Adaptive Optics Scanning Laser Ophthalmoscopy” Optom. Vis Sci. 87(4) 260-268 (2010) [link to OVS website to access Supplemental Digital Content]

Tam, J., Martin, J.A., Roorda, A., "Non-invasive visualization and analysis of parafoveal capillaries in humans" Invest.Ophthalmol.Vis.Sci. 51 (3): 1691-1698 (2010)

Rossi, E.A., Roorda, A.,"The relationship between visual resolution and cone spacing in the human fovea” Nature Neuroscience, 13: 156–157 (2010)  [supplemental information] [video1][video2] [video3]
2009

Sincich, L.C., Zhang, Y., Tiruveedhula, P., Horton, J.C., Roorda, A., “Resolving single cone inputs to visual receptive fields” Nature Neuroscience, 12(8) 967-969 (2009) [supplemental information]  [video1]  [video2]

Li K.Y., Mishra, S., Tiruveedhula, P. & Roorda, A., "Comparison of control algorithms for a MEMS-based adaptive optics scanning laser ophthalmoscope," Proceedings of the 2009 American Control Conference, St. Louis, June 10-12, 2009

Yoon, M.K., Roorda, A., Zhang, Y., Nakanishi, C., Wong, L.J., Zhang, Q., Gillum, L., Green, A., & Duncan, J.L. (2008). “Adaptive optics scanning laser ophthalmoscopy images demonstrate abnormal cone structure in a family with the mitochondrial DNA T8993C mutation”.  Invest Ophthalmol.Vis.Sci. 50(4):1838-1847 (2009)

Martin, J.A., Roorda, A. “Pulsatility of Parafoveal Capillary Leukocytes” Exp Eye Res. 88(3). 356-360 (2009)

2008

Raghunandan, A., Frasier, J., Poonja, S., Roorda, A., & Stevenson, S. B. “Psychophysical measurements of referenced and unreferenced motion processing using high-resolution retinal imaging” J. Vision, 8(14):14, 1-11 (2008)

Grieve, K., Roorda, A. "Intrinsic signals from human cone photoreceptors" Invest.Ophthalmol.Vis.Sci. 49(2) 713-719 (2008)
2007

Ramamirtham,R., Kee,C.S., Hung,L.F., Qiao-Grider,Y., Huang,J., Roorda,A., & Smith,E.L., III “Wave aberrations in rhesus monkeys with vision-induced ametropias.”  Vision Res. 47, 2751-2766. (2007)

Arathorn D. W., Yang Q., Vogel C. R., Zhang Y., Tiruveedhula P., and Roorda A., "Retinally stabilized cone-targeted stimulus delivery," Opt. Express 15, 13731-13744 (2007)

Duncan,J.L., Zhang,Y., Gandhi,J., Nakanishi,C., Othman,M., Branham,K.H., Swaroop,A., & Roorda,A. "High resolution imaging with adaptive optics in patients with inherited retinal degenerations using adaptive optics."  Invest.Ophthalmol.Vis.Sci. 48: 3283-3291 (2007)

Rossi, E.A., Weiser, P., Tarrant, J., Roorda, A., "Visual Performance in Emmetropia and Low Myopia After Correction of High Order Aberrations" J. Vision  7(8): 14 (2007)

Roorda,A., Zhang,Y., & Duncan,J.L. "High-resolution in vivo imaging of the RPE mosaic in eyes with retinal disease."  Invest.Ophthalmol.Vis.Sci. 48(5): 2297-2303 (2007)

Vilupuru, A.S., Rangaswamy,N.V., Frishman, L.J., Smith III, E.L., Harwerth, R.S., and Roorda, A. “Adaptive Optics Scanning Laser Ophthalmoscopy for in vivo Imaging of Lamina Cribrosa” J. Opt.. Soc. Am. A. 24(5): 1417-1425 (2007)

Li. K.Y., Roorda, A., “Automated Identification of Cones in Adaptive Optics Fundus Images” J. Opt.. Soc. Am. A. 24(5): 1358-1363 (2007)

Zhang, Y., Roorda, A., “Photon Signal Detection and Evaluation in the Adaptive Optics Scanning Laser Ophthalmoscope” J. Opt. Soc. Am. A. 24(5): 1276-1283 (2007)
2006

Grieve, K. Tiruveedhula, P., Zhang, Y., Roorda, A., “Multi-wavelength Imaging with the Adaptive Optics Scanning Laser Opthalmoscope” Optics Express 14(25), 12230-12242 (2006)

Ramamirtham, R., Kee, C., Hung, L., Qiao-Grider, Y., Roorda, A., Smith III, E.L., “Monochromatic Ocular Aberrations in Young Monkeys” Vision Research. 46(21) 3616-3633 (2006)

 

Roorda, A., Garcia, C.A., Martin, J.A., Poonja, S., Queener, H., Romero-Borja, F., Sepulveda, R., Venkateswaran, K., Zhang, Y., “What can adaptive optics do for a scanning laser ophthalmoscope?” Bulletin de la Société belge d'ophtalmologie 302(4) 231-244 (2006).

Wolfing, J.I., Chung, M., Carroll, J., Roorda, A., Williams, D.R., “High-Resolution Retinal Imaging of Cone-Rod Dystrophy” Ophthalmology, 113(6) 1014-1019 (2006)

Zhang, Y., Poonja, S., Roorda, A. "MEMS-based Adaptive Optics Scanning Laser Ophthalmoscopy" Optics Letters, 31, 1268-1270 (2006)

Zhang, Y., Roorda, A. “Evaluating the Lateral Resolution of the Adaptive Optics Scanning Laser Ophthalmoscope” Journal of Biomedical Optics, 11, 014002 (2006)

Vogel, C.R., Arathorn, D.W., Roorda, A., Parker, A. "Retinal Motion Estimation in Adaptive Optics Scanning Laser Ophthalmoscopy" Optics Express, 14(2): 487-497 (2006)

2005 and earlier
Martin, J.A., Roorda, A., “Direct and Non-Invasive Assessment of Parafoveal Capillary Leukocyte Velocity” Ophthalmology 112(12) 2219-2224 (2005)

Poonja, S., Patel, S., Henry, L., Roorda, A., “Dynamic visual stimulus presentation in an adaptive optics scanning laser ophthalmoscope” Journal of Refractive Surgery 21(5): 575-580 (2005)

Romero-Borja, F., Venkateswaran, K., Hebert, T.J., Roorda, A. “Optical Slicing of Human Retinal Tissue in vivo with the Adaptive Optics Scanning Laser Ophthalmoscope” Applied Optics 44(19): 4032-4040 (2005)

Christou, J.C., Roorda, A., Williams, D.R., “Deconvolution of Adaptive Optics Retinal Images” J. Opt. Soc. Am. A 21(8) 1393-1401 (2004)

Kee, C., Hung, L., Qiao-Grider,Y., Roorda, A., Smith III, E.L. “Effects of Optically Imposed Astigmatism on Emmetropization in Monkeys” Invest.Ophthalmol.Vis.Sci. 45(6): 1647-1659 (2004)

Vilupuru, A., Roorda, A., Glasser, A. “Spatially Variant Changes in Lens Power During Ocular Accommodation in a Rhesus Monkey Eye” J.Vision 4(4), 299-309 www.journalofvision.org/4/4/6 (2004)

Cheng, H., Barnett, J.K., Vilupuru, A.S., Marsack, J.D., Kasthurirangan, S., Applegate, R.A., Roorda, A. “A Population Study on Changes in Wave Aberration with Accommodation” J.Vision 4(4), 272-280 http://www.journalofvision.org/4/4/3 (2004)

Roorda, A., Glasser, A. “Wave Aberrations of the Isolated Crystalline Lens” J.Vision 4(4), 250-261 www.journalofvision.org/4/4/1 (2004)

Venkateswaran, K., Romero-Borja, F., Roorda, A. “Theoretical Modeling and Evaluation of the Axial Resolution of the Adaptive Optics Scanning Laser Ophthalmoscope” J. Biomed. Opt. 9(1): 132-138 (2004)  [pdf ]

Martin, J.A., Roorda, A. "Predicting and Assessing Visual Performance with Multizone Bifocal Contact Lenses" Opt. Vision Sci. 80(12): 812-819 (2003)

Donnelly III, W.J., Roorda, A. “The Optimal Pupil Size in the Eye for Axial Resolution” J. Opt. Soc Am. A. 20(11): 2010-2015 (2003)

Roorda, A., Williams, D.R. "Optical Fiber Properties of Individual Human Cones" Journal of Vision, 2: 404-412 (2002)
Roorda, A., Romero-Borja, F., Donnelly III, W.J., Queener, H., Hebert, T.J., Campbell, M.C.W. "Adaptive Optics Scanning Laser Ophthalmoscopy" Opt. Express 10(9) 405-412 (2002)
Wilson, B.J., Decker, K.E., Roorda, A., "Monochromatic Aberrations Provide and Odd-Error Cue to Focus Direction" J.Opt.Soc.Am.A. 19(5) 833-839 (2002).
Roorda, A., Metha, A., Lennie, P., Williams, D.R., “Packing Arrangement of the Three Cone Classes in the Primate Retina” Vision Research, 41(12) 1291-1306 (2001).
Brainard, D.H., Roorda, A., Yamauchi, Y., Calderone, J.B., Metha, A.B., Neitz, M., Neitz, J., Williams, D.R., Jacobs, G.H. "Functional consequences of individual variation in relative L and M cone numerosity".  J. Opt. Soc. Am. A 17: 607-614 (2000). [pdf of errata]
Roorda, A., Williams, D.R., "The Arrangement of the Three Cone Classes in the Living Human Eye" Nature 397, 520-522 (1999)
Roorda, A., Campbell, M.C.W., Bobier, W.R., “An Infrared Eccentric Photo-optometer” Vision Research 38:1913-1924 (1998)
Roorda, A., Bobier, W.R., Campbell, M.C.W., “Slope-based Eccentric Photorefraction: Theoretical Analysis of Different Light Source Configurations and Effects of Ocular Aberrations” J. Opt. Soc. Am. A. 14: 2547-2556 (1997)
  Roorda, A., Bobier,W.R., "Retinoscopic reflexes: theoretical basis and effects of monochromatic aberrations", J. Am. Opt. Ass. 67: 610-618 (1996)
Roorda, A., Bobier, W.R., "Geometrical Technique to Determine the Influence of Monochromatic Aberrations on Retinoscopy", J. Opt. Soc. Am. A. 13: 3-11 (1996)
Roorda, A., Campbell, M.C.W., Bobier, W.R.,  "Geometrical Theory to Predict Eccentric Photorefraction Intensity Profiles in the Human Eye", J. Opt. Soc. Am. A. 12:1647-1656 (1995)
Campbell, M.C.W., Bobier, W.R., Roorda, A.,  "The Effect of Monochromatic Aberrations on Photorefractive Patterns", J. Opt. Soc. Am. A. 12:1637-1646 (1995)

Book Chapters

Miller, D.T. & Roorda, A. “Adaptive Optics in Retinal Microscopy and Vision ” chapter 15 in Handbook of Optics (Optical Society of America) (2009)

Roorda, A. Miller, D.T., Christou, J.C. "Strategies for High Resolution Retinal Imaging" Chapter 10 in Adaptive Optics for Vision Science: Principles, Practices, Design and Applications (Porter, J., Queener, H., Lin, J., Thorn, K., Awwal, A.A.W. eds) Wiley, (2006)
Venkateswaran, K., Romero-Borja, F., Roorda, A., "Design of an Adaptive Optics Scanning Laser Ophthalmoscope" Chapter 16 in Adaptive Optics for Vision Science: Principles, Practices, Design and Applications (Porter, J., Queener, H., Lin, J., Thorn, K., Awwal, A.A.W. eds) Wiley, (2006)
Roorda, A., Venkateswaran, K, Romero-Borja, F., Williams, D.R., Carroll, J., Hofer, H.J., "Adaptive Optics Ophthalmoscopy" , Chapter 9 in Retinal Imaging (Huang, D., Kaiser, P.K., Lowder, C.Y., Traboulsi, E.I. eds) Mosby Elsevier Philadelphia, PA, pp. 125-133 (2006)
Roorda, A. “A Review of Optics” chapter 2 in Wavefront Customized Visual Correction: The Quest for SuperVision II. (Macrae, S.M., Krueger, R.R., Applegate, R.A., ed). Slack Inc. Thorofare, NJ (2004)

Roorda, A., Williams, D.R. “Retinal Imaging Using Adaptive Optics” chapter 5 in Wavefront Customized Visual Correction: The Quest for SuperVision II. (Macrae, S.M., Krueger, R.R., Applegate, R.A., ed). Slack Inc. Thorofare, NJ (2004)

Roorda, A. "Human Visual System - Image Formation" in: Vol. 1 of The Encyclopedia of Imaging Science and Technology, Editor Joseph P. Hornak,(John Wiley & Sons, New York) pp 539-557 (ISBN #0-471-33276-3) (2002). [pdf ]
Roorda, A., Williams, D.R., “Retinal Imaging Using Adaptive Optics” chapter 4 in Customized Corneal Ablation: The Quest for SuperVision. (Macrae, S.M., Krueger, R.R., Applegate, R.A., ed). Slack Incorporated, Thorofare, NJ, pp. 41-50. (2001)
Williams, D.R., Roorda, A. "The Trichromatic Mosaic in the Human Eye" Chapter 5 in: Color Vision: From Genes to Perception.  (Gegenfurtner, K. & Sharpe, L.T., eds) Cambridge University Press, New York. pp. 111-120 (1999)
Williams, D.R. Liang, J., Miller, D.M., Roorda, A. “Wavefront sensing and compensation for the human eye” in Adaptive Optics Engineering Handbook (R.K. Tyson ed.) Marcel Dekker, New York pp. 287-310 (2000)

Other Publications

Read, S.A., Williams, D.R., Wojtkowski, M., Roorda, A., Nichols, J.J., Mutti, D.O., Kaufman, P.L., Carney, L.G. "Imaging and measurement in the eye: now and ahead" Optom.Vis.Sci. 89, 521-523. (2012). [pdf]

Stevenson, S.B., Roorda, A., Kumar, G., “Eye Tracking with the Adaptive Optics Scanning Laser Ophthalmoscope” Proceedings of the 2010 Symposium on Eye-Tracking Research & Applications, Austin, TX, March 22-24,2010 (ACM, NY) pp: 495-498 [pdf]

Myers, R.A., Farrell, R., Zhang, Y., Roorda, A., “Near Infrared Receiver for Advanced Ophthalmology” Ophthalmic Technologies XX, edited by Fabrice Manns, Per G. Söderberg, Arthur Ho, Proc. of SPIE Vol. 7550 (2010)

Carroll, J., Drexler, W., & Roorda, A., "Advances in Retinal Imaging: Introduction," J. Opt. Soc. Am. A 24(5): 1223-1224 (2007) [pdf ]

Grieve K., Tirveedhula, P., Zhang, Y., Roorda, A., “Functional imaging with the multi-wavelength adaptive optics scanning laser ophthalmoscope” in Ophthalmic Technologies XVII, edited by edited by Fabrice Manns, Per Soderberg, Arthur Ho, Proceedings of SPIE Vol. 6426A. (SPIE, Bellingham, WA, 2007), paper# 6426A-57.[pdf]

Zhang, Y., Poonja, S., Roorda, A. “AOSLO: from Benchtop to Clinic” in Advanced Wavefront Control: Methods, Devices, and Application IV, edited by Giles, M.K., Gonglewski, J.D., Carreras, R.A., Proceedings of SPIE Vol. 6306 (SPIE, Bellingham, WA, 2006), paper 63060V. (August, 2006) [pdf]

Zhang, Y., Roorda, A. “MEMS deformable mirror for ophthalmic imaging” in MEMS/MOEMS Components and Their Applications III, edited by Scot S. Olivier, Srinivas A. Tadigadapa, Albert K. Henning , Proceedings of SPIE Vol. 6113 (SPIE, Bellingham, WA, 2006), paper#6113-10. [pdf ]

Zhang, Y., Poonja, S., Roorda, A. “Adaptive Optics Scanning Laser Ophthalmoscope using a Micro-electro-mechanical (MEMS) Deformable Mirror” in Ophthalmic Technologies XVI, edited by Fabrice Manns, Per Soderberg, Arthur Ho, Proceedings of SPIE Vol. 6138 (SPIE, Bellingham, WA, 2005), paper# 61380Z. [pdf ]

Stevenson, S.B., Roorda, A., “Correcting for Miniature Eye Movements in High Resolution Scanning Laser Ophthalmoscopy” in Ophthalmic Technologies XV, edited by Fabrice Manns, Per Soderberg, Arthur Ho, Proceedings of SPIE Vol. 5688A (SPIE, Bellingham, WA, 2005), 145-151. [pdf ]

Carroll, J., Gray, D.C., Roorda, A., Williams, D.R., “Recent Advances in Retinal Imaging with Adaptive Optics” Optics and Photonics News (Optical Society of America, Washington, DC) January: 36-42 (2005). [pdf ].

Roorda, A., Williams, D.R. “Adaptive Optics and Retinal Imaging” OSA Trends in Optics and Photonics Vol. 35, Vision Science and its Applications, Lakshminarayanan,V. (ed) (Optical Society of America, Washington, DC 2000), pp: 151-162.
Roorda, A. “Adaptive Optics Ophthalmoscopy,” Journal of Refractive Surgery  2000, 16(5): 602-607 (2000).
Applegate, R.A., Thibos, L.N., Bradley, A., Marcos, S., Roorda, A., Salmon, T.O., Atchison, D.A. "Reference Axis Selection: Subcommittee Report of the OSA Working Group to Establish Standards for Measurement and Reporting of Optical Aberrations of the Eye," Journal of Refractive Surgery  2000, 16(5): 656-658 (2000).
Thibos, L. Applegate, R.A., Schweigerling, J.T., Webb, R. VSIA Standards Taskforce Members, "Report from the VSIA Taskforce on Standards for Reporting the Optical Aberrations of the Eye," Journal of Refractive Surgery  2000, 16(5): 654-655 (2000).
Thibos, L. Applegate, R.A., Schweigerling, J.T., Webb, R. VSIA Standards Taskforce Members, "Standards for Reporting the Optical Aberrations of Eyes" OSA Trends in Optics and Photonics Vol. 35, Vision Science and its Applications, Lakshminarayanan,V. (ed) (Optical Society of America, Washington, DC 2000), pp: 232-244.
Roorda, A., Neitz, J. “Chromatic Topography of the Retina”, editorial introduction for J. Opt Soc. Am. A feature issue on Chromatic Topography of the Retina 17: 495-496 (2000) [pdf ]
Roorda, A., Bobier,W.R., “On the Matter of Stops in Retinoscopy and Photorefraction,” J. Am. Opt. Ass. 69: 621-624 (1998).
Roorda, A., Williams, D.R. “New Directions in Imaging the Retina” Optics and Photonics News, (monthly publication of the Optical Society of America, Washington, D.C.) 8 (2):23-29 (1997)